1,4-DIPOLAR CYCLOADDITION REACTIONS IN ORGANIC SYNTHESIS :SYNTHESIS OF SOME NEW N-ARYLPHTHALIMIDES AND FULLY SUBSTITUTED PYRROLO[3,4-H] QUINOLINE DERIVATIVES

Abstract

#N-Arylphthalimides 3a-e were prepared through the reaction of 2- mino-3-cyano-4-ethoxycarbonyl-5-methylfuran 1 and N-Arylmaleimides 2a-e. Compounds 3a-e reacted with malononitrile, cyanoacetophenone, cyanothioacetamide and ethylcyanoacetate to give the corresponding pyrrolo[3,4-h] quinoline derivatives 4a-e, 5a-e, 6a-e and 7a-e respectively. The structure of the newly synthesized compounds was established on the basis of elemental analysis and spectral data studies.