Synthesis, Spectroscopic Characterization And Biological Activity Of Metal Complexes With A New Schiff Bases As A Ligand

Abstract

#A new series of VO(II), Mn(II), Fe(III), Co(II), Ni(II), Cu(II), Zn(II), ZrO(II), Ru(III), Sn(II), Cd(II), Ho(III) Ti(II) and UO₂(II) complexes of (E)-2-(p-toluidino)-N'-(2-hydroxbenzylidene) acetohydrazide have been synthesized and characterized by elementals analyses, H¹-NMR, IR, UV- Vis. spectra, magnetic moments and conductance measurements. The IR data show that the ligand behaves monobasic tridentate or dibasic tridentate towards the metal ion. Molar conductances in DMF solution indicate that the complexes are non-electrolytes. Antibacterial and antifungal tests of the ligand and some of its metal complexes revealed that, the complexes are more potent bactericides and fungicides than the ligand.